Using nickel to fold discrete synthetic macromolecules into single-chain nanoparticles

Author:

Reith Melissa A.1,Kardas Sinan23ORCID,Mertens Chiel1,Fossépré Mathieu2ORCID,Surin Mathieu2ORCID,Steinkoenig Jan1ORCID,Du Prez Filip E.1ORCID

Affiliation:

1. Polymer Chemistry Research Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Faculty of Sciences, Ghent University, Krijgslaan 281 S4-bis, Ghent B-9000, Belgium

2. Laboratory of Chemistry of Novel Materials, Center of Innovation in Materials and Polymers (CIRMAP), University of Mons - UMONS, Place du Parc 20, Mons B-7000, Belgium

3. Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, Eindhoven 5600 MB, The Netherlands

Abstract

Sequence-defined macromolecules were prepared with a thiolactone-based platform whereby ligand functionalities were introduced along the backbone enabling a nickel induced formation of single-chain nanoparticles.

Funder

Fonds De La Recherche Scientifique - FNRS

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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