Discovery of a pyruvylated peptide-metabolizing enzyme using a fluorescent substrate-based protein discovery technique
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences
2. The University of Tokyo
3. Bunkyo-ku
4. Japan
5. Precursory Research for Embryonic Science and Technology (PRESTO)
6. Drug Discovery Initiative
7. Graduate School of Medicine
Abstract
We employed a fluorescent substrate-based target discovery approach to characterize an acylamino acid-releasing enzyme (APEH) as a pyruvylated peptide-metabolizing enzyme.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC00829A
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