β-Hairpins as peptidomimetics of human phosphoprotein-binding domains
Author:
Affiliation:
1. UCIBIO
2. Departamento de Química
3. Faculdade de Ciências e Tecnologia
4. Universidade Nova de Lisboa
5. 2829-516 Caparica
6. Aix Marseille Univ
7. CNRS
8. Centrale Marseille
9. iSm2
10. Marseille
Abstract
Highly selective affinity reagents based on beta-hairpin cyclic peptides were designed to mimic the natural interactions between phosphoprotein-binding domains and their cognate targets.
Funder
Fundação para a Ciência e a Tecnologia
Centre National de la Recherche Scientifique
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00564A
Reference47 articles.
1. Fluorescence recognition of proteinaceous binders in works of art by a novel integrated system of investigation
2. Affinity adsorbents for proline-rich peptide sequences: a new role for WW domains
3. Affinity chromatography techniques based on the immobilisation of peptides exhibiting specific binding activity
4. β-Hairpin Peptidomimetics: Design, Structures and Biological Activities
5. Synthetic Peptides as Protein Mimics
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