Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(<scp>iv</scp>) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells-Reference-Cited by-同舟云学术

Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(iv) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells

Published:2023 Issue:19 Volume:5 Page:5399-5413
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Sedky Nada K.¹^ORCID,Braoudaki Maria²,Mahdy Noha Khalil³,Amin Kenzy⁴,Fawzy Iten M.⁵^ORCID,Efthimiadou Eleni K.⁶^ORCID,Youness Rana A.⁷⁸,Fahmy Sherif Ashraf⁴^ORCID

Affiliation:

1. Department of Biochemistry, School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, R5 New Garden City, New Administrative Capital, Cairo, Egypt

2. Department of Clinical, Pharmaceutical, and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK

3. Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, 11562 Cairo, Egypt

4. Department of Chemistry, School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, R5 New Garden City, New Capital, Cairo 11835, Egypt

5. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, 11835 Cairo, Egypt

6. Inorganic Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou 157 71, Greece

7. Biology and Biochemistry Department, Faculty of Biotechnology, German International University (GIU), New Administrative Capital, Cairo, Egypt

8. Department of Biology and Biochemistry, School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, R5 New Garden City, New Administrative Capital, Cairo, Egypt

Abstract

This study reports the design of thermo-responsive nanoliposomes loaded with asplatin using Box–Behnken design for the effective treatment of triple-negative breast cancer.

Funder

Royal Society of Chemistry

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D3NA00368J

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