Diverse privileged N-polycyclic skeletons accessed from a metal-free cascade cyclization reaction

Author:

Li Wenzhong1,Wang Yu1,Qi Huijing1,Shi Ran1,Li Jiazhu1ORCID,Chen Si1ORCID,Xu Xin-Ming1ORCID,Wang Wei-Li2

Affiliation:

1. College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China

2. School of Chemistry and Materials Science, Ludong University, Yantai 264005, China

Abstract

Metal-free cascade cyclization of 2-acylbenzoic acids with amines provided a one-pot synthesis of diverse isoindoloisoquinoline and benzoindolizinoindole derivatives, which were subsequently used to produce nitrogen-containing nine-membered ring compounds.

Funder

Yantai University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference70 articles.

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