Extending the shelf life of HLM chips through freeze-drying of human liver microsomes immobilized onto thiol–ene micropillar arrays
Author:
Affiliation:
1. Faculty of Pharmacy, Drug Research Program, University of Helsinki, Finland
2. Faculty of Health Sciences, School of Pharmacy, University of Eastern Finland, Finland
3. Helsinki Institute of Sustainability Science, University of Helsinki, Finland
Abstract
Funder
NordForsk
Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta
Business Finland
Publisher
Royal Society of Chemistry (RSC)
Link
http://pubs.rsc.org/en/content/articlepdf/2024/LC/D4LC00429A
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1. Predicting in vivo drug interactions from in vitro drug discovery data
2. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
3. In Vitro Evaluation of Reversible and Irreversible Cytochrome P450 Inhibition: Current Status on Methodologies and their Utility for Predicting Drug–Drug Interactions
4. Drug glucuronidation assays on human liver microsomes immobilized on microfluidic flow-through reactors
5. The material-enabled oxygen control in thiol-ene microfluidic channels and its feasibility for subcellular drug metabolism assays under hypoxia in vitro
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