Isotope-dilution LC-MS/MS analysis of the elastin crosslinkers desmosine and isodesmosine in acute cerebral stroke patients-Reference-Cited by-同舟云学术

Isotope-dilution LC-MS/MS analysis of the elastin crosslinkers desmosine and isodesmosine in acute cerebral stroke patients

Published:2022 Issue:49 Volume:12 Page:31769-31777
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mikagi Ayame¹^ORCID,Tashiro Ryosuke²^ORCID,Inoue Tomoo¹²³^ORCID,Anzawa Riki¹,Imura Akiho¹,Tanigawa Takahiro¹,Ishida Tomohisa³,Inoue Takashi³,Niizuma Kuniyasu⁴⁵^ORCID,Tominaga Teiji²,Usuki Toyonobu¹^ORCID

Affiliation:

1. Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo 102-8554, Japan

2. Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

3. Department of Neurosurgery, Sendai Medical Center, 2-11-12 Miyagino, Miyagino-ku, Sendai 983-8520, Japan

4. Department of Neurosurgical Engineering and Translational Neuroscience, Graduate School of Biomedical Engineering, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

5. Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan

Abstract

Established isotope-dilution LC-MS/MS method suggested that desmosines can be regarded as biomarkers of acute cerebral stroke.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA06009D

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1. Extracellular matrix 4: The elastic fiber