Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors-Reference-Cited by-同舟云学术

Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors

Published:2011 Issue:11 Volume:9 Page:4144
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Guasconi Margherita,Lu Xiaoyun,Massarotti Alberto,Caldarelli Antonio,Ciraolo Elisa,Tron Gian Cesare,Hirsch Emilio,Sorba Giovanni,Pirali Tracey

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2011/OB/C1OB05336A

Reference32 articles.

1. The Protein Kinase Complement of the Human Genome

2. Protein kinases — the major drug targets of the twenty-first century?

3. Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

4. Protein Kinase Inhibitors: Insights into Drug Design from Structure

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