A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints-Reference-Cited by-同舟云学术

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A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints

Published:2018 Issue:1 Volume:9 Page:307-319
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Moreno-Ulloa Aldo¹²³⁴⁵^ORCID,Nájera-García Nayelli⁶⁷⁸⁹,Hernández Marcela⁶⁷⁸⁹,Ramírez-Sánchez Israel¹²³⁴⁶,Taub Pam R.¹²³⁴,Su Yongxuan¹²¹⁰⁴,Beltrán-Partida Ernesto¹¹¹²¹³⁹,Ceballos Guillermo⁶⁷⁸⁹^ORCID,Dugar Sundeep¹⁴¹⁵⁴,Schreiner George¹⁴¹⁵⁴,Best Brookie M.¹¹⁶²⁴,Ciaraldi Theodore P.¹²³⁴¹⁷,Henry Robert R.¹²³⁴¹⁷,Villarreal Francisco¹²³⁴

Affiliation:

1. University of California

2. San Diego

3. School of Medicine

4. USA

5. Departamento de Innovación Biomédica

6. Escuela Superior de Medicina del Instituto Politécnico Nacional

7. Sección de Posgrado

8. México City

9. Mexico

10. Chemistry and Biochemistry

11. Universidad Autónoma de Baja California

12. Facultad de Odontología

13. Mexicali

14. Cardero Therapeutics

15. Inc.

16. Skaggs School of Pharmacy and Pharmaceutical Sciences

17. San Diego VA Health Care System

Abstract

We reported that (−)-epicatechin can stimulate mitochondria biogenesis and improve metabolism.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FO/C7FO01028A

Reference35 articles.

1. Prevalence of the Metabolic Syndrome in the United States, 2003-2012

2. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

3. Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

4. Impact of glucose-lowering drugs on cardiovascular disease in type 2 diabetes

5. Long-Term Use of Cardiovascular Drugs

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