Metal–organic framework-based oxygen carriers with antioxidant activity resulting from the incorporation of gold nanozymes-Reference-Cited by-同舟云学术

Metal–organic framework-based oxygen carriers with antioxidant activity resulting from the incorporation of gold nanozymes

Published:2023 Issue:7 Volume:11 Page:2551-2565
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Liu Xiaoli¹,Domingues Nency Patricio²^ORCID,Oveisi Emad³^ORCID,Coll-Satue Clara¹^ORCID,Jansman Michelle Maria Theresia¹^ORCID,Smit Berend²^ORCID,Hosta-Rigau Leticia¹^ORCID

Affiliation:

1. DTU Health Tech, Center for Nanomedicine and Theranostics, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800 Kgs. Lyngby, Denmark

2. Laboratory of Molecular Simulation (LSMO), Institute of Chemical Sciences and Engineering (ISIC), École Polytechnique Fédérale de Lausanne (EPFL)-Valais, CH-1950 Sion, Switzerland

3. Interdisciplinary Centre for Electron Microscopy (CIME), École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

Abstract

We present a novel oxygen therapeutic where hemoglobin is encapsulated within metal–organic framework nanocarriers. Antioxidant gold nanozymes are also being entrapped within the platform to minimize the conversion of Hb into nonfunctional metHb.

Funder

Teknologi og Produktion, Det Frie Forskningsråd

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01405J

Reference53 articles.

1. A review of the application of autologous blood transfusion

2. Transfusion Medicine — Blood Transfusion

3. Stepping stones to the future of haemoglobin-based blood products: clinical, preclinical and innovative examples