The synthesis of cardenolide and bufadienolide aglycones, and related steroids bearing a heterocyclic subunit-Reference-Cited by-同舟云学术

The synthesis of cardenolide and bufadienolide aglycones, and related steroids bearing a heterocyclic subunit

Published:2017 Issue:4 Volume:34 Page:361-410
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Michalak Michał¹²³⁴,Michalak Karol¹²³⁴,Wicha Jerzy¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Polish Academy of Sciences

3. 01-224 Warsaw

4. Poland

Abstract

Cardenolides and bufadienolides constitute an attractive class of biologically active steroid derivatives which have been used for the treatment of heart disease in traditional remedies as well as in modern medicinal therapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NP/C6NP00107F

Reference298 articles.

1. L. F. Fieser and M.Fieser, Steroids, Reinhold, New York, 1959

2. Chemical Synthesis of the Cardiotonic Steroid Glycosides and Related Natural Products

3. Synthetic Cardenolides and Related Compounds

4. Digoxin in the Management of Cardiovascular Disorders

5. Digitalis Therapy for Patients in Clinical Heart Failure

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