Stereoselective synthesis of 2-trifluoromethylated and 2-difluoromethylated dihydrofurans via organocatalytic cascade Michael/alkylation reaction-Reference-Cited by-同舟云学术

Stereoselective synthesis of 2-trifluoromethylated and 2-difluoromethylated dihydrofurans via organocatalytic cascade Michael/alkylation reaction

Published:2021 Issue:13 Volume:8 Page:3260-3267
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Dong Xiaodi¹²³⁴⁵,Wang Wei¹²³⁴⁵^ORCID,Li Huang¹²³⁴⁵,Xu Qiya¹²³⁴⁵,Ye Ling⁶⁷⁸⁵,Li Xinying¹²³⁴⁵,Zhao Zhigang¹²³⁴⁵,Li Xuefeng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Basic Chemistry of the State Ethnic Commission

2. College of Chemistry and Environment

3. Southwest Minzu University

4. Chengdu 610041

5. China

6. Faculty of Geosciences and Environmental Engineering

7. Southwest Jiaotong University

8. Chengdu 610031

Abstract

A highly stereoselective cascade Michael/alkylation process has been established to construct 2-trifluoromethylated and 2-difluoromethylated dihydrofurans.

Funder

Department of Science and Technology of Sichuan Province

National Natural Science Foundation of China

Southwest Minzu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00367D

Reference59 articles.

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2. Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

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4. Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

5. The Many Roles for Fluorine in Medicinal Chemistry

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