Cancer-microenvironment triggered self-assembling therapy with molecular blocks

Author:

Nakatsuji Hirotaka1234ORCID,Shioji Yudai56234,Hiraoka Noboru56234,Okada Yuta56234,Kato Natsuko56234,Shibata Sayaka7894,Aoki Ichio7894,Matsusaki Michiya12345ORCID

Affiliation:

1. Joint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry

2. 2-1 Yamadaoka

3. Suita city

4. Japan

5. Division of Applied Chemistry

6. Osaka University Graduate School of Engineering

7. National Institute for Quantum and Radiological Science and Technology

8. 4-9-1 Anagawa Inage

9. Chiba city

Abstract

Molecular blocks (4-MB) were designed to circulate as a single molecule or as a few molecules in blood vessels and self-assemble in response to a tumor specific conditions, as a cancer therapeutic agent.

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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