Development of a bio-electrospray system for cell and non-viral gene delivery

Author:

Lee Myung Chul1234,Seonwoo Hoon5674,Garg Pankaj8294,Jang Kyoung Je1234,Pandey Shambhavi8294,Kim Hong Bae1234,Park Sang Bae1234,Ku Jong Beom1234,Kim Jang Ho101112134,Lim Ki Taek1415164,Chung Jong Hoon12348ORCID

Affiliation:

1. Department of Biosystems & Biomaterials Science and Engineering

2. Seoul National University

3. Seoul 151-742

4. Republic of Korea

5. Department of Industrial Machinery Engineering

6. Sunchon National University

7. Suncheon

8. Research Institute for Agriculture and Life Sciences

9. Seoul

10. Department of Biosystems Engineering

11. College of Agricultural and Life Sciences

12. Kangwon National University

13. Chuncheon 200-701

14. Department of Rural and Biosystems Engineering

15. Chonnam National University

16. Gwangju 500-757

Abstract

The NVG-BES system facilitated to introduce DNA to cells and delivered cells to a target simultaneously. In this method, a cationic polymer was used as non-viral carrier with electric force by bio-electrospray (BES) system to electrospray living cells onto a target.

Funder

National Research Foundation of Korea

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries

Ministry of Science, ICT and Future Planning

Ministry of Agriculture, Food and Rural Affairs

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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