Amplification-free detection of telomerase activity at the single-cell level <i>via</i> Cas12a-lighting-up single microbeads (Cas12a-LSMBs)-Reference-Cited by-同舟云学术

Amplification-free detection of telomerase activity at the single-cell level via Cas12a-lighting-up single microbeads (Cas12a-LSMBs)

Published:2023 Issue:21 Volume:23 Page:4674-4679
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Wang Honghong¹^ORCID,Wang Shuhui¹,Wang Hui¹^ORCID,Tang Fu²^ORCID,Chen Desheng¹,Liang Yuanwen¹,Li Zhengping¹^ORCID

Affiliation:

1. Beijing Key Laboratory for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing 100083, China

2. School of Materials Science and Engineering, University of Science and Technology Beijing, 30 Xueyuan Road, Haidian District, Beijing 100083, China

Abstract

Amplification-free and ultrasensitive detection of telomerase activity at the single-cell level via Cas12a-lighting-up single microbeads (Cas12a-LSMBs).

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00598D

Reference44 articles.

1. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

2. The Structure and Function of Telomerase Reverse Transcriptase

3. Observation of processive telomerase catalysis using high-resolution optical tweezers

4. Structure and function of telomeres

5. Four faces of cellular senescence

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