Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3-Reference-Cited by-同舟云学术

Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3

Published:2022 Issue:19 Volume:13 Page:9973-9987
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Liu Zhendong¹²^ORCID,Liu Ruizhou¹,Wang Rui²,Dai Jihang¹,Chen Hui¹,Wang Jingcheng¹,Li Xiaolei¹

Affiliation:

1. Clinical Medical College of Yangzhou University, Northern Jiangsu People's Hospital, Yangzhou, 225001, China

2. Qilu hospital of Shandong University Dezhou Hospital, Dezhou, 253000, China

Abstract

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degeneration, subchondral bone sclerosis, synovial hyperplasia and osteophyte formation as the main pathological manifestations.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01304E

Reference42 articles.

1. Osteoarthritis

2. Subchondral bone as a key target for osteoarthritis treatment

3. Cellular senescence in knee osteoarthritis: molecular mechanisms and therapeutic implications

4. The relative contribution of mechanical stress and systemic processes in different types of osteoarthritis: the NEO study

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