The first catalyst and solvent-free synthesis of 2-arylimidazo[2,1-b][1,3,4]thiadiazoles: a comparative assessment of greenness-Reference-Cited by-同舟云学术

The first catalyst and solvent-free synthesis of 2-arylimidazo[2,1-b][1,3,4]thiadiazoles: a comparative assessment of greenness

Published:2015 Issue:55 Volume:5 Page:44353-44360
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wadhwa Preeti¹²³⁴,Kaur Tanpreet¹²³⁴,Sharma Anuj¹²³⁴

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology Roorkee

3. Roorkee-247667

4. India

Abstract

A one-pot, three-component, catalyst and solvent free synthesis of imidazo[2,1-b][1,3,4]thiadiazoles utilizing 5-aryl-1,3,4-thiadiazol-2-amines, aldehydes and isonitriles has been developed. The “greenness” was successfully evaluated within the ambits of green metrics.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06747B

Reference29 articles.

1. P. A. Jacobi , in Advances in Heterocyclic Natural Product Synthesis, ed. W. H. Pearson, Jai Press, Greenwich, CT, 1992, vol. 2, p. 251

2. Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target

3. Chemistry of imidazo[2,1-b][1,3,4]thiadiazoles

4. Recent Advances in the Chemistry and Synthetic Uses of Amino-1,3,4-thiadiazoles

5. 2,5,6-Trisubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for antihyperlipidemic agents

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. “In-Water” Three-Component One-Pot Reaction for the Facile Synthesis of Densely Functionalized 2,3-Dihydro-1H-pyrrol-2-ols and Mechanistic Insight;ACS Sustainable Chemistry & Engineering;2024-08-22

2. Green Synthesis of Thiazoles and Thiadiazoles Having Anticancer Activities under Microwave Irradiation;Current Microwave Chemistry;2024-07-18

3. Cu-catalysed diversity-oriented synthesis of isoxazole and imidazo[1,2-a]azine conjugates;Tetrahedron;2024-02

4. Synthesis and Biological Evaluation of Fused Thiazolotriazole and Imidazothiadiazole Scaffolds;S-Heterocycles;2024

5. Recent synthetic strategies of medicinally important imidazothiadiazoles;Journal of Saudi Chemical Society;2023-07