Fruit bromelain ameliorates rat constipation induced by loperamide-Reference-Cited by-同舟云学术

Fruit bromelain ameliorates rat constipation induced by loperamide

Published:2017 Issue:72 Volume:7 Page:45252-45259
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhou Zijuan¹²³⁴,Wang Liang¹²³⁴,Xu Ming⁵²³⁴,Yin Lianhong⁵²³⁴,Yang Fang²³⁴,Hui Simei²³⁴,Yi Yanlin²³⁴,Feng Panpan¹²³⁴,Wang Jingyu¹²³⁴,Lin Yuan⁵²³⁴,Peng Jinyong⁵²³⁴,Chen Dapeng¹²³⁴^ORCID

Affiliation:

1. Laboratory Animal Center

2. Dalian Medical University

3. Dalian 116044

4. China

5. College of Pharmacy

Abstract

Fruit bromelain ameliorates rat constipation. MLCK, myosin light chain kinase; p-MLC₂₀, phosphorylation of 20 kDa myosin light chain.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA06109A

Reference32 articles.

1. [38] Pineapple cysteine endopeptidases

2. Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice

3. Bromelain: biochemistry, pharmacology and medical use

4. Bromelain improves decrease in defecation in postoperative rats: Modulation of colonic gene expression of inducible nitric oxide synthase

5. Inhibitory effects of bromelain, a cysteine protease derived from pineapple stem (Ananas comosus), on intestinal motility in mice

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