Abstract
Although the monocyclic pyrimidine and bicyclic purine ring systems are the information-conferring elements in both DNA and RNA, there are small molecule variants that have distinct biological functions. These include the purine alkaloids theophylline and caffeine, the 7-deazaguanines, the plant alkylated adenine cytokinins, the antitumor and antiviral arabinosyl adenine (AraA), blastocidin S, sinefungin, tunicamycin, and several variants of peptidyl nucleosides.
Publisher
The Royal Society of Chemistry