A CLINICAL STUDY TO EVALUATE THE EFFICACY OF MANJISHTADYA TAILA AND Its MODIFIED FORM OF CREAM IN TWAK VAIVARNYA

Abstract

External beauty has gained a lot of attention & demand in ancient times as well as in today’s era. Twak Vaivarnya refers to the abnormal pigmentation of the skin, often resulting in uneven patches or dark spots. It is a common disorder affecting any age group. It affects the sex invariably. It is not limited to any particular class of society. Vyanga (dark spots on face) is a condition of localized hyper melanosis which affects only the skin of the face. Topical applications mentioned in modern cosmetics containing synthetic or chemical substances are known to have several adverse effects including local hypersensitivity reactions. Hence, there is always a demand for safe and effective topical applications to manage hyperpigmented skin diseases. A total of 30 candidates were selected for the present study. In Control Group 15 candidates were given classically prepared Manjishtadya taila and in Study Group 15 candidates were given with Manjishtadya taila cream in Randomized open label parallel group exploratory study. A comparative clinical study was planned into Twak vaivarnya to elicit whether the modified tropical dosage form is showing equal or comparable clinical efficacy in clinical scenario. The MASI score was considered to assess the effect of treatment. Score was compared before and after treatment both in Group A and Group B, highly significant result was observed with P-0.000. In the present study, Manjishtadya taila and Manjishtadya taila cream both showed equal effectiveness, but statistically Manjishtadya taila had better results.