Author:
Badyal Sakshi,Dang Poonam,Dhawan Puneet,Shekhar Tiwari Himanshu
Abstract
T. Renal KFT is a poly herbo-metallic composition in tablet form which includes a total of 24 herbs and properly
processed metals which is used to treat symptoms of CKD including oedema, reduced urinary output, anemia and
other associated symptoms. These herbs are selected in such a way which are been used in traditional sciences
since long back. The aim of this study is to evaluate the possible mode of action of the composition based on the
classical properties mentioned in the textbooks and also evaluating its pharmacological and biological activities.
Classical textbooks, API, Various databases and search engines were used to screen and extract the related data.
All the herbs and metals used in the formulation possess numerous active constituents which are responsible for
exhibiting multiple actions such as Anti-inflammatory, Diuretic, Anti-lithiatic, Anti-anaemic, Hepato-protective,
Immunomodulatory activities etc. Hence, this can be used as a potent alternative for the various associated
symptoms of CKD.
Publisher
International Ayurvedic Medical Journal
Reference82 articles.
1. 1. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3(1):1–150.
2. 2. Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). 2022 Apr;12(1):7-11. doi: 10.1016/j.kisu.2021.11.003. Epub 2022 Mar 18. PMID: 35529086; PMCID: PMC9073222.
3. 3. Joanne M. Bargman and Karl Skorecki: Chronic kidney disease. Harrison's Principles of Internal Medicine-17th edition (2008) Vol-2 Chapter no.280: 2308-2321.
4. 4. Kaul, R., Ray, A. C. and Dutt, S. 1929. Constitution of the active principal of Embelia ribes. I. J Indian Chem Soc 6, 577-586.
5. 5. Haq, K., Ali, M. and Siddiqui, A. W. 2005. New com-pounds from the seeds of Embelia ribes Burm. Phar-mazie 60, 69-71.