MECHANISM OF ACTION OF THE HEAVY METAL IONS ON THE PHYSICOCHEMICAL PROPERTIES OF PHOSPHOLIPIDS
Author:
Shishkina L.1, Beletskaya P.2, Dubobik A.3, Mashukova A.1, Shvydkiy V.1
Affiliation:
1. N.M. Emanuel Institute of Biochemical Physics of Russian Academy of Sciences 2. N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences 3. Emanuel Institute of Biochemical Physics of Russian Academy of Sciences
Abstract
Effect of the divalent copper and iron ions on their ability to form complexes with phospholipids and the lipid peroxidation processes intensity, to affect the self-aggregation of the natural lipids in the water medium and ξ-potential of formed particles are studied in the wild range of the metal ion concentrations. Mathematical analysis of UV-spectra of the water solutions of lecithin, metal ions and their mixtures by Gauss method is revealed that copper and iron ions form complexes with phospholipids and act on content of the oxidation products. Besides, the scale of effect depends on the ion concentration, its nature and the lipid oxidizability. The absence of the linear dependence of the ξ-potential value for the lecithin particles on the ion concentration in the water medium and the essential differences of their ability to act on size of formed by lecithin aggregates are obtained. The obtained data allow us to conclude that quality of the natural water is due to both concentrations of the heavy metal ions and their ability to act on the lipid peroxidation regulatory system parameters of the inherent in water bio-objects.
Publisher
RIOR Publishing Center
Reference15 articles.
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