Author:
Lee Mijoon,Hesek Dusan,Noll Bruce C.,Oliver Allen G.,Mobashery Shahriar
Abstract
The compound 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane, C15H14O3S2, a selective gelatinase inhibitor, was synthesized and structurally characterized. Two crystals were analyzed, one each for theRandSenantiomers, and the results were compared with the previously reported structure of the racemate. The enantiomerically pure compounds both crystallize withZ′ = 2 in the space groupP21, while the racemic mixture crystallizes withZ′ = 1 in the space groupP21/c, with disorder in the position of the thiirane group. This disorder accommodates both molecules for each of the enantiomerically pure crystals, showing good overlap of the molecules of the pure enantiomorphs with the components of the centrosymmetric structure.
Publisher
International Union of Crystallography (IUCr)
Subject
Materials Chemistry,Inorganic Chemistry,Physical and Theoretical Chemistry,Condensed Matter Physics
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献