Abstract
The crystal structures of the hydrochloride salts of nine substituted tryptamines, namely, 1-methyltryptammonium chloride, C11H15N2
+·Cl−, (1), 2-methyl-1-phenyltryptammonium chloride, C17H19N2
+·Cl−, (2), 5-methoxytryptammonium chloride, C11H15N2O+·Cl−, (3), 5-bromotryptammonium chloride, C10H12BrN2
+·Cl−, (4), 5-chlorotryptammonium chloride, C10H12ClN2
+·Cl−, (5), 5-fluorotryptammonium chloride, C10H12FN2
+·Cl−, (6), 5-methyltryptammonium chloride, C11H15N2
+·Cl−, (7), 6-fluorotryptammonium chloride, C10H12FN2
+·Cl−, (8), and 7-methyltryptammonium chloride, C11H15N2
+·Cl−, (9), are reported. The seven tryptamines with N—H indoles, (3)–(9), show very similar structures, with N—H...Cl hydrogen-bonding networks forming two-dimensional sheets in the crystals. These sheets are combinations of R
4
2(8) and R
4
2(18) rings, and C
2
1(4) and C
2
1(9) chains. Substitution at the indole N atom reduces the dimensionality of the hydrogen-bonding network, with compounds (1) and (2) demonstrating one-dimensional chains that are a combination of different rings and parallel chains.
Funder
National Science Foundation, Directorate for Mathematical and Physical Sciences
Publisher
International Union of Crystallography (IUCr)
Subject
Materials Chemistry,Inorganic Chemistry,Physical and Theoretical Chemistry,Condensed Matter Physics
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. N-Cyclohexyltryptamine: freebase, bromide and fumarate;Acta Crystallographica Section E Crystallographic Communications;2023-07-25
2. Crystal structure of serotonin;Acta Crystallographica Section E Crystallographic Communications;2022-03-10