Abstract
This review describes the development and application of a new crystallographic technique that is starting to enable the three-dimensional structural determination of molecules in their photo-activated states. So called `photocrystallography' has wide applicability, particularly in the currently exciting area of photonics, and a discussion of this applied potential is put into context in this article. Studies are classified into four groups: photo-structural changes that are (i) irreversible; (ii) long-lived but reversible under certain conditions; (iii) transient with photo-active lifetimes of the order of microseconds; (iv) very short lived, existing at the nanosecond or even picosecond level. As photo-structural changes relative to the `ground state' can be subtle, this article necessarily concentrates on small-molecule single-crystal X-ray diffraction given that high atomic resolution is possible. That said, where it is pertinent, references are also made to related major advances in photo-induced macromolecular crystallography. The review concludes with an outlook on this new research area, including the future possibility of studying even more ephemeral, femtosecond-lived, photo-active species.
Publisher
International Union of Crystallography (IUCr)
Reference93 articles.
1. Femtosecond time-resolved powder diffraction experiments using hard X-ray free-electron lasers
2. Feasibility and Realization of Single-Pulse Laue Diffraction on Macromolecular Crystals at ESRF
3. BowesK. F., ColeJ. M., HusheerS. L. G., RaithbyP. R., SavareseT. L., SparkesH. A., TeatS. J. & WarrenJ. E. (2006). Chem. Commun. pp. 2448–2450.
4. Bowes, K. F., Cole, J. M., Husheer, S. L. G., Raithby, P. R., Sparkes, H. A., Teat, S. J. & Warren, J. E. (2008). J. Synchrotron Rad. In the press.
5. BrinkmanW. F. & PintoM. R. (1997). Bell Labs Tech. J. pp. 57–75.
Cited by
65 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献