Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin-Reference-Cited by-同舟云学术

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin

Published:2011-10-19 Issue:11 Volume:67 Page:920-928
ISSN:0907-4449
Container-title:Acta Crystallographica Section D Biological Crystallography
language:
Short-container-title:Acta Crystallogr D Biol Cryst

Author:

Abdulmalik Osheiza,Ghatge Mohini S.,Musayev Faik N.,Parikh Apurvasena,Chen Qiukan,Yang Jisheng,Nnamani Ijeoma,Danso-Danquah Richmond,Eseonu Dorothy N.,Asakura Toshio,Abraham Donald J.,Venitz Jurgen,Safo Martin K.

Publisher

International Union of Crystallography (IUCr)

Subject

General Medicine,Structural Biology

Link

http://journals.iucr.org/d/issues/2011/11/00/ea5150/ea5150.pdf

Reference29 articles.

1. 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells

2. Vanillin, a potential agent for the treatment of sickle cell anemia

3. How Allosteric Effectors Can Bind to the Same Protein Residue and Produce Opposite Shifts in the Allosteric Equilibrium

4. Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes

5. Bisaldehyde Allosteric Effectors as Molecular Ratchets and Probes

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Red Blood Cells as Therapeutic Target to Treat Sickle Cell Disease;Antioxidants & Redox Signaling;2024-01-23

2. Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde;Pharmaceutics;2023-10-28

3. Targeted modification of furan‐2‐carboxaldehydes into Michael acceptor analogs yielded long‐acting hemoglobin modulators with dual antisickling activities;Chemical Biology & Drug Design;2023-10-05

4. Exploring the Structural Importance of the C3═C4 Double Bond in Plant Alkaloids Harmine and Harmaline on Their Binding Interactions with Hemoglobin;ACS Omega;2023-09-28

5. X-ray crystallography and sickle cell disease drug discovery—a tribute to Donald Abraham;Frontiers in Molecular Biosciences;2023-05-24