SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SCHIFF BASE DERIVED FROM GLYCINE AND 4-CHLOROBENZOPHENONE AND ITS METALS COMPLEXES OF Cr(II) and Co(II)

Author:

Khalid Halima,Hussaini Sunusi Y.,Hasheem Khatan A.,Panda Najib A.

Abstract

The Schiff base ligand was synthesized using glycine and 4-chlorobenzophenone, and then reacted with metal salt of chromium, and cobalt to form the complex of the metals. The ligand and the complexes were characterized using IR-spectrophotometer, and peaks were analysed which confirmed the formation of (M-N) and (M-O) bond in the complexes at around 503- 847, also solubility test, water of crstallisation, magnetic susceptibility, melting Point and conductivity of the ligand and complexes were carried out in the research. Lastly, the compound were tested against some strain of bacteria(Salmonella typhi, Staphylococcus aureus, Escherichia coli) in which the activity of the ligand and some complex were detected in the bacteria, the  cobalt complex showed higher activity than the chromium complex and the ligand.

Publisher

Federal University Dutsin-Ma

Subject

General Medicine

Reference17 articles.

1. Aliyu H. N. and Adamu H. (2010). Spectroscopic and potentiometric studies of Co(ii) and Ni(ii) complexes with N-(1-morpholinobenzyl) semicarbazide. Bayero journal of pure and applied sciences.3(2):9-15

2. Amit R. Y., Vijaya V. D., Gaurav, B. P. and Anand, S. A. (2014). Synthesis, characterization, biological and electrical conductivity studies of some Schiff base metal complexes. Journal of chemical society Ethiopia. 28(2):255-264

3. Benabdallah T., Ali H. and Hasnia R. (2004). Spectrophotometric studies of the behavior of multidentate Schiff base ligands with copper(ii) in methanol solution. African journal of chemistry. (57):33-36

4. Brdowska K. and Elzbieta L. C. (2014). Schiff bases-interesting range of application in various field of sciences. Journal of chemical society. 2(68):129-134

5. Muhammad A. R., Shahid S. and Shafiq U. R. (2009). Synthesis, characterization and antimicrobial potential of transition metal complexes of triacetic lactone. African Journal of Biotechnology 8(19):5116-51

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3