ISOLATION OF SQUALENE FROM DICHLOROMssETHANE EXTRACT OF CROTON NIGRITANUS LEAF-Reference-Cited by-同舟云学术

ISOLATION OF SQUALENE FROM DICHLOROMssETHANE EXTRACT OF CROTON NIGRITANUS LEAF

Published:2024-04-30 Issue:2 Volume:8 Page:212-216
ISSN:2616-1370
Container-title:FUDMA JOURNAL OF SCIENCES
language:
Short-container-title:FJS

Author:

Abdullahi Abdullahi Muhammad,Nkemakonam Olime M.,Garba Usman,Mustapha Muhammad A.,Nazifi Muhammad I.,Usman Muhammad B.,Ibrahim Umar M.

Abstract

A precursor of steroids with a variety of biological activities is squalene. The purpose of the study was to identify and describe the industrial/medical chemical found in Croton nigritanus. Using the solvents such as; dichloromethane, ethyl acetate, and n-hexane, the procedure entails a liquid-liquid extraction stage using the partition method and a solid-liquid extraction step using the maceration method. For separation and purification, gravity column chromatography (GCC) and thin-layer chromatography were employed. The isolated chemical's identity was determined using FTIR, 1H NMR and GC-MS spectroscopy. The inquiry successfully extracted and analyzed the major chemical compound which was identified as Squalene.

Publisher

Federal University Dutsin-Ma

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