A New Method for Detecting Urinary Bladder Cancer by Using FDG PET/CT-Reference-Cited by-同舟云学术

A New Method for Detecting Urinary Bladder Cancer by Using FDG PET/CT

Published:2014-08 Issue:4 Volume:13 Page:369-376
ISSN:1533-0346
Container-title:Technology in Cancer Research & Treatment
language:en
Short-container-title:Technol Cancer Res Treat

Author:

Chen Yen-Kung¹²,Yeh Chung-Hsin³²,Su Chen-Tau⁴,Tsui Chih-Cheng¹,Cheng Ru-Hwa¹,Hung Guang-Uei⁵,Kao Chia-Hung⁶⁷

Affiliation:

1. Department of Nuclear Medicine and PET Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan

2. School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan

3. Division of Urology, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan

4. Department of Medical Imaging, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan

5. Department of Nuclear Medicine, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan

6. Graduate Institute of Clinical Medicine Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan

7. Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan

Abstract

To evaluate the accuracy of a new fluorine-18-2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) method when applying an increased upper limit of the image threshold (IULIT) to detect bladder cancer. All patients with an unknown history of bladder tumors were retrospectively included for analysis. Applying an IULIT in PET showed a hypermetabolic focus. 18F-FDG accumulation in the bladder that was higher or lower than the urinary level of 18F-FDG was considered an abnormal focus. In 12 of the 28,767 patients with bladder cancer, applying an IULIT in PET allowed the visualization of the contrast between lesion and urinary activity. The proposed method could increase the accuracy of detection of bladder cancer.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology

Link

http://journals.sagepub.com/doi/pdf/10.7785/tcrt.2012.500383

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