CYTOLOGICAL DIAGNOSIS OF FINE-NEEDLE PUNCTURE BIOPSIES OF THE THYROIDGLAND IN UKRAINE: COMPARIS ON WITH INTERNATIONAL PRACTICE

Abstract

Thyroid cancer is one of the few cancers diagnosed by cytological examination of thin nodule puncture biopsies. To achieve standardization of diagnostic terminology, morphological criteria and risk of malignancy in the whole world, the 6-level Bethesda system is used. The work aimed to analyze the results of cytological examination of fine-needle aspiration puncture biopsies (TAPBs) of thyroid nodules according to the international Bethesda system for the last three years and compare them with the world practice. As a result, 5687 surveys were conducted, where the proportion of women was 87.9% and of men 12.1%. Of all the cases, the most extensive cytological findings were of class II (benign formation) - 3061 studies (57%). The number of cases interpreted as class III was within the reference values, i.e. 8.2%. The fourth class accounted for 8.2%, the fifth for 3.5%, and the sixth for 5.0%. In total, these three classes account for 17.2%. Our analysis compared the reference values and data from other laboratories revealed comparable results. The analysis of the structure of the results of cytological investigations according to Bethesda revealed a high rate of the first class (non-informative), which indicates the need for more accurate interaction between clinical physicists and cytologists.