Biological effect of nanodiamonds and soot on structural and functional conditions of chiken embryo kidneys

Abstract

The biological impact of nano-sized materials on kidneys of chicken embryos obtained from incubation of eggs from High-Line white was researched. Suspension of nanodiamonds and soot on bio-friendly dextrane was injected into the yolk sac of embryos on the third day of incubation and the condition of kidney tissues on the 14 th and 20 th days of incubation was studied. Under the same conditions as experimental groups the eggs from the control group with injection of pure dextrane were incubated. The alteration effect of both researched materials on excretory organs of the embryo was shown. They cause edema, dystrophy and formation of calcificates. The increase of the kidney channels epithelium area due to proteinosis and edema of epitheliocytes was statistically proved for both experimental groups.