Affiliation:
1. Taras Shevchenko National University of Kyiv
Abstract
In recent years much attention has been paid for study of the melatonin use possibilities for improving obesity comorbidities. The aim of our study was to determine the influence of melatonin different time treatment on body weight changes of dietinduced obesity in rats. The administration by gavage of melatonin in dose 30 mg/kg for 7 weeks had the potential to decrease visceral fat weight, Lee index (both after morning and evening treatment) and body weight gain rate (only after evening dose).
Publisher
Taras Shevchenko National University of Kyiv
Subject
General Medicine,General Chemistry
Reference48 articles.
1. Fleming T., Robinson M., Thomson B., Graetz N., Margono C., et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. The lancet. 2014; 384(9945): 766-781.
2. The official data of the WHO Bulletin published in May 2017. Available from: http://www.who.int
3. Lumeng C., Saltiel A. Inflammatory links between obesity and metabolic disease. J Clin Invest. 2011; 121: 2111–2118.
4. Mathieu P., Poirier P., Pibarot P., Lemieux I., Després JP. Visceral obesity the link among inflammation, hypertension, and cardiovascular disease. Hypertension. 2009; 53(4): 577–584.
5. McTiernan A. Obesity and cancer: the risks, science, and potential management strategies. Oncology 2005; 19(7): 871–881.
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