OPTIMIZATION OF CHEMOTHERAPY OF MALIGNANT TUMORS BASED ON DELIVERY OF DRUGS WITH ENHANCED CONVECTION-Reference-Cited by-同舟云学术

OPTIMIZATION OF CHEMOTHERAPY OF MALIGNANT TUMORS BASED ON DELIVERY OF DRUGS WITH ENHANCED CONVECTION

Published:2022 Issue:1 Volume: Page:83-91
ISSN:2706-9680
Container-title:Journal of Numerical and Applied Mathematics
language:
Short-container-title:JNAM

Author:

Stelya O. B., ,Klyushin D. A.,

Abstract

The article describes a numerical method for optimizing the chemotherapy of malignant tumors on the basis of drug delivery using increased convection. The problem of optimal control with point sources for reaching the desired intratumor distribution of drugs in macroscopic scale granting the properties of intersticial space and effects of convective diffusion is considered. The efficiency of proposed algorithm for optimal control is shown.

Publisher

Taras Shevchenko National University of Kyiv

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