Mathematical dynamics for HIV infections with public awareness and viral load detectability

Author:

MUSTAPHA Umar Tasiu1ORCID,ADO Abdurrahman1ORCID,YUSUF Abdullahi1ORCID,QURESHİ Sania2ORCID,MUSA Salihu Sabiu3ORCID

Affiliation:

1. Department of Mathematics, Federal University Dutse, 7156 Jigawa

2. Department of Basic Sciences and Related Studies, Mehran University of Engineering and Technology, Jamshoro 76062

3. Department of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong SAR

Abstract

In this paper, we develop a nonlinear deterministic model that incorporates public awareness and treatment to describe the dynamics of HIV/AIDS in an infected population with detectable and undetectable viral load. The model undergoes backward bifurcation in which a stable disease-free equilibrium coexists with a stable endemic equilibrium. Numerical simulations carried out show the behavior of the state variables and the impact of public awareness in controlling the spread of HIV. The results show that public awareness will help in curtailing the spread of HIV infection, and when treatment is applied to infected individuals with detectable viral load can easily suppress their virus to become undetectable so that they cannot transmit HIV through sexual intercourse.

Publisher

Mathematical Modelling and Numerical Simulation with Applications

Reference29 articles.

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2. Wilson, D.P., Law, M.G., Grulich, A.E., Cooper, D.A. and Kaldor, J.M. Relation between HIV viral load and infectiousness: a model-based analysis. The Lancet, 372(9635), 314-320, (2008).

3. Center for Disease Control and Prevention. About HIV https://www.cdc.gov/hiv/basics/whatishiv.html, (2021).

4. World Health Organization. HIV and AIDS www.who.int/news-room/fact-sheets/detail/hiv-aids, (2021).

5. HIV.gov. The Global HIV and AIDS Epidemic https://www.hiv.gov/hiv-basics/overview/data-andtrends/global-statistics, (2021).

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