Microbic eczema – trigger points of influence

Abstract

The relevance of microbic eczema is caused by prevalence of a disease, a long chronic current, frequent, is long the proceeding recurrence, insufficiently studied pathogeny and difficulties of the choice of effective treatment. Microbic eczema – the chronic recurrent dermatosis which is characterized by evolutionary polymorphism of elements of rash, wet an itch and a peculiar allergic reaction of the sensibilized skin to decomposition products of microorganisms and their toxins arising against the background of it is long the existing piogenic center at disturbance of the major regulatory systems of an organism. At patients with microbic eczema disbioz skin it is shown by reduction of a share of S. epidermidis, Bifidobacterium spp., Lactobaccilus spp. and significant increase in opportunistic and pathogenic flora, associations of mushrooms quite often meet representatives of obligate flora. Allergenic action of S. aureus and fungal microflora, in particular, of C. Albicans at microbic eczema considerably amplify in the conditions of a mikstinfektion. In recent years microbic eczema tends to a heavy current with a frequent long recurrence, considerable distribution of process on skin and is characterized by resistance to the standard methods of treatment. Elimination of action of microbic, mycotic dissimination and normalization of a biocenosis of skin at microbic eczema are the key principle of treatment of patients interfering recuring of chronic eczema. The article focuses on microbial eczema, as the most difficult type of eczema in therapy, presents our own clinical observations of the course of microbial eczema of various localization and severity, and also shows the effectiveness of the Russian-made topical drug Akriderm GK, containing a micronized form of betamethasone dipropionate, gentamicin sulfate and clotrimazole in the complex therapy of patients with microbial eczema.