The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis

Author:

Karakashian N. R.1,Manukhina E. I.1,Gevorgyan M. A.1,Manukhin I. B.1

Affiliation:

1. First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Abstract

The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function

Publisher

Remedium, Ltd.

Subject

General Medicine

Reference13 articles.

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2. Kulakov V.I., Korneeva I.E. Sovremennye podkhody k diagnostike i lecheniyu zhenskogo besplodiya. Akush i ginekol. 2002. 2: 56-59.

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4. Adamyan L.V., Gasparyan S.A. Genital'nyi endometrioz. Sovremennyi vzglyad na problemu. 2004. S. 228.

5. Adamyan L.V., Kulakov V. I., Andreeva E.N. Endometriozy. 2006. S 18

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