Affiliation:
1. Pirogov Russian National Research Medical University; Moscow Centre for Research & Practice in Medical Rehabilitation, Restorative and Sports Medicine
2. Moscow Centre for Research & Practice in Medical Rehabilitation, Restorative and Sports Medicine
3. Pirogov Russian National Research Medical University
Abstract
Introduction. Transient ischemic attacks can be a predictor of a more severe cardiovascular event, the risk of which depends on many factors that requires a personalized approach. Neuropsychological disorders (cognitive, emotional) have a significant impact on quality of life and social activity and are often underestimated in patients with TIA. Comprehensive medical rehabilitation with the inclusion of antithrombotic therapy and psychocorrection measures may reduce the risk of recurrent cardiovascular events in patients with TIA.Purpose of the study: to substantiate the efficiency of complex medical and non-pharmacological rehabilitation in patients who underwent TIA by analyzing the characteristics of the main and leading concomitant diseases.Materials and methods. The morbidity of 351 TIA patients was studied and analyzed. The average age of the examined patients was 58.6 ± 2.2 years, there were 64.9% of women and 35.1% of men. All patients received an individualized medical rehabilitation program for 12 months with correction of identified neuropsychological disorders. Depending on background and concomitant diseases the antiplatelet or anticoagulants therapy was differently administrated.Results and dicussion. Psychological, cognitive, and physical disorders (based on subjective complaints) are common in patients with TIA. The prevalence of mental disorders in patients with TIA was 138.2 cases per 100 patients. The correction of cognitive impairment, depressive symptoms is associated with improved quality of life (p < 0.05). Repeated acute cerebrovascular events (TIA, ischemic stroke) were recorded during the first 6 months after TIA in 29 patients (10.4%) with severe stenosis of the brachiocephalic arteries, severe arterial hypertension and paroxysmal atrial fibrillation.Conclusion. The importance of comprehensive medical and social rehabilitation of patients with TIA is determined. The participation of a psychotherapist as a member of a multidisciplinary team is necessary. A significant role of the secondary prevention of acute cerebrovascular events is assigned to rational antithrombotic therapy.
Reference48 articles.
1. Uchiyama S., Amarenco P., Minematsu K., Wong K.S.L. (eds.). TIA as Acute Cerebrovascular Syndrome. Frontiers of Neurology and Neuroscience. Basel, Karger; 2014. Vol. 33. https://doi.org/10.1159/isbn.978-3-318-02459-3.
2. Simmons B.B., Cirignano B., Gadegbeku A.B. Transient ischemic attack: Part I. Diagnosis and evaluation. Am Fam Physician. 2012;86(6):521-526. Available at: https://pubmed.ncbi.nlm.nih.gov/23062043/
3. Johnston S.C. Clinical practice. Transient ischemic attack. N Engl J Med. 2002;347(21):1687-1692. https://doi.org/10.1056/NEJMcp020891.
4. Gupta H., Farrell A., Mittal M. Transient ischemic attacks: predictability of future ischemic stroke or transient ischemic attack events. Ther Clin Risk Manag. 2014;10:27-35. https://doi.org/10.2147ACRM.S54810.
5. Johnston S.C., Rothwell P.M., Nguyen-Huynh M.N., Giles M.F., Elkins J.S., Bernstein A.L., Sidney S. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet. 2007;369(9558): 283-292. https://doi.org/10.1016/S0140-6736(07)60150-0.
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