Affiliation:
1. Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)
Abstract
Allergic rhinitis is a global public health problem at the present stage, given the high prevalence, the formation of therapy-resistant phenotypes, high comorbidity and the negative impact on all aspects of a patient’s life. Histamine is one of the main mediators of allergy, and therefore drugs number one in the treatment of patients with AR of all options are antihistamine drugs or H1-blockers. The innovative antihistamine drug of the second generation levocetirizine (Allerway®) prevents the development and facilitates the course of allergic reactions, also has anti-inflammatory and antiallergic action. Allerway® is bioequivalent to the original drug, has broad indications for use, has established itself as an effective drug with a good safety profile.
Reference33 articles.
1. Kim C.H., Kim J.K., Kim H.J., Cho J.H., Kim J.S., Kim Y.D. et al. Comparison of intranasal ciclesonide, oral levocetirizine, and combination treatment for allergic rhinitis. Allergy Asthma Immunol Res. 2015 Mar;7(2):158-66.
2. Kawauchi H., Yanai K., Wang D.Y., Itahashi K., Okubo K. Antihistamines for Allergic Rhinitis Treatment from the Viewpoint of Nonsedative Properties. Int J Mol Sci. 2019 Jan 8;20(1). pii: E213.
3. Zhang Y., Zhang L. Increasing Prevalence of Allergic Rhinitis in China. Allergy Asthma Immunol Res. 2019 Mar;11(2):156-169.
4. Akhouri S., House S.A. Allergic Rhinitis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.2019 Mar 1. PMID:30844213.
5. Small P., Keith P.K., Kim H. Allergic rhinitis. Allergy Asthma Clin Immunol. 2018 Sep 12;14(Suppl 2):51.