Clopidogrel as a part of double disaggregant therapy in ACS: a reasonable choice in complex clinical situations

Author:

Kashtalap V. V.1,Barbarash O. L.1

Affiliation:

1. Federal State Budgetary Institution «Research Institute for Complex Issues of Cardiovascular Diseases»; Federal State Budget Educational Institution of Higher Education «Kemerovo State Medical University» the Ministry of Health of the Russian Federation.

Abstract

Based on the recommendations of the European Heart Society and the results of clinical and register studies, the article highlights the complex issues that arise when prescribing antiplatelet therapy in patients with acute coronary syndrome, including with concomitant atrial fibrillation (AF); the promising strategies for managing the risk of ischemic and hemorrhagic events are described. Also a clinical case of a patient with acute coronary syndrome and AF is presented, illustrating the objective complexity of correct selection of antiplatelet therapy in such patients.

Publisher

Remedium, Ltd.

Subject

General Medicine

Reference41 articles.

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2. Barbarash O.L., Kashtalap V.V. The place of pharmacoinvasive management in patients with ST-elevation acute Coronary syndrome in Russia. Kardiologiia. 2014;54(9):79-85. (In Russ.)

3. Barbarash O.L. European program «Stent for life initiative»: background, history, aims and goals. Complex Issues of Cardiovascular Diseases. 2013;1:10-18. (In Russ.)

4. Erlikh A.D. Dual antiplatelet therapy: needs for compliance to therapy and possibilities its increase. Atherothrombosis. 2014;2:25-33. (In Russ.)

5. Barbarash O.L., Karetnikova V.N., Kashtalap V.V. The patient after myocardial infarction: how to reduce a risk of recurrent ischemic event? Cardiosomatics. 2015;6(2):12-19. (In Russ.)

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