Effective treatment of skin and metabolic manifestations of hyperandrogenism: a comprehensive improvement of quality of life

Abstract

Clinical manifestations of hyperandrogenism can be an important diagnostic symptom of polycystic ovary syndrome, and in most cases allow establishing this diagnosis in a timely manner. The article discusses the problem of acne not only in adolescence, but also in adult women, and the problem of hirsutism in detail. It shows the role of combined oral contraceptives (COCs) as an effective therapy for acne and hirsutism in women, as well as the first-line therapy for polycystic ovary syndrome, according to the international and national clinical guidelines. The data summarize the effectiveness of the use of COCs containing drospirenone as a gestagenic component and levomefolate calcium in order to compensate for folate deficiency and, accordingly, reduce the level of homocysteine, which is often elevated in women with hyperandrogenism.