Possibilities of symptomatic treatment of allergic rhinitis in children

Abstract

This article presents an overview of current views on the problem of allergic rhinitis in children. Modern data on the epidemiology of allergic rhinitis and basic comorbid conditions are covered. The issue of patient routing with suspicion of allergic rhinitis and the main directions in the treatment of this disease is briefly discussed. On the basis of the data of the latest consensus papers, the role of various medication therapy for allergic rhinitis has been evaluated: first and second generation antihistamines, intranasal glucocorticosteroids, leukotriene receptor antagonists, and mast cell membrane stabilizers. Possibilities of symptomatic nasal obstruction therapy in case of allergic rhinitis with the help of nasal vasoconstrictor drugs (decongestants) have been assessed in more detail. The basics of pharmacokinetics and pharmacodynamics of decongestants are presented, as well as the data of a clinical study demonstrating the efficacy and safety of the combined preparation of phenylephrine and dimethindene maleate in the symptomatic treatment of allergic rhinitis in children. On the basis of the presented material it is concluded that timely diagnosis and further management of patients with allergic rhinitis in accordance with the principles reflected in modern clinical guidelines, in most cases, allow to effectively control the course of the disease, maintaining the quality of life of patients at a high level.