Complex therapy of contact dermatitis: from theory to practice

Abstract

This article discusses the relevance of the causes and further development of contact dermatitis. In accordance with the clinical recommendations of the Ministry of Health of the Russian Federation, simple irritable contact dermatitis is an acute or chronic inflammatory skin disease caused by the irritating effect of environmental factors on the skin. Allergic contact dermatitis is an acute or chronic inflammatory skin disease that occurs in response to skin contact with substances that can cause sensitization and specific allergic inflammation. Allergic contact dermatitis can develop because of a reaction to absolutely any substance. This is a common pathology among skin diseases, manifested by polymorphic symptoms and its regression as the etiological factor and appropriate therapy disappear. The mechanisms of development of various forms of dermatitis are described, the immunological disorders that occur in this pathology are indicated, the clinical features are indicated. The publication examines various clinical cases of somatically healthy patients suffering from simple contact and allergic dermatitis caused by variant factors, with localization of the pathological process in the facial area. According to the doctor’s prescription, patients used traditional therapy regimens consisting of external/topical treatment and general therapy, strictly in accordance with clinical recommendations. Topical glucocorticosteroids are the first line of therapy for contact dermatitis and it is extremely important to choose modern drugs with a high safety profile when localizing foci on the face. At the end of the course of treatment, patients noted a significant improvement in the condition of the dermis in the form of minimizing the manifestations of erythema of the skin, the disappearance of polymorphic skin rash elements, and the disappearance of exfoliation.