Affiliation:
1. Scientific Center of Neurology; Russian University of Medicine (ROSUNIMED)
2. Russian University of Medicine (ROSUNIMED)
Abstract
Introduction. Extraction of mandibular third molars is one of the most common oral surgical procedures.Aim. To evaluate the efficacy of B Complex Preparation on pain and sensory problems related to inferior alveolar nerve damage after surgical removal of mandibular third molars.Materials and methods. In the open-label comparative trial 86 patients aged 45 to 54 years with sensory disturbances, lasting 72 hours, after surgical removal of mandibular third molar were included. Pain intensity was assessed using a visual analogue scale (VAS). Quantitative sensory testing (QST) was performed with the computer-controlled Thermal Sensory Analyzer (TSA type II, Medoc Ltd., Ramat Yishai, Israel) with contact thermode (30 × 30 mm). Patients with inferior alveolar nerve damage were divided into 2 groups: the first group – 44 patients received the standart therapy in combination with B Complex Preparation for 30 days, in the second group 42 patients received the standart treatment.Results. After a course of treatment in the first group (B Complex Preparation) was determined the relieving of numbness and pain in 90.9% of patients with inferior alveolar nerve damage. The pain intensity in VAS reduced from 6.3 ± 0.9 to 0.8 ± 0.2 points (p = 0.02) in the first group and from 6.1 ± 0.6 to 4.8 ± 0.4 points (p = 0.09) in the second group. Only in the first group there was a decrease of the warm sensation threshold during QST, which additionally confirms the positive therapeutic effect of B Complex Preparation.Conclusion. Effectiveness of therapy with B Complex Preparation was noted in patients with algic manifistations and sensory disorders after the removal of the third molar.