Matrix Protein 2 Vaccination and Protection against Influenza Viruses, Including Subtype H5N1

Author:

Tompkins Stephen Mark1,Zhao Zi-Shan1,Lo Chia-Yun1,Misplon Julia A.1,Liu Teresa1,Ye Zhiping1,Hogan Robert J.2,Wu Zhengqi1,Benton Kimberly A.1,Tumpey Terrence M.3,Epstein Suzanne L.1

Affiliation:

1. Food and Drug Administration, Bethesda, Maryland, USA;

2. University of Georgia, Athens, Georgia, USA;

3. Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Publisher

Centers for Disease Control and Prevention (CDC)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

Reference22 articles.

1. Heterologous protection against influenza by injection of DNA encoding a viral protein.;Ulmer;Science,1993

2. Vaccination with DNA encoding internal proteins of influenza virus does not require CD8(+) cytotoxic T lymphocytes: either CD4(+) or CD8(+) T cells can promote survival and recovery after challenge.;Epstein;Int Immunol,2000

3. DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice.;Epstein;Emerg Infect Dis,2002

4. Lamb RA, Krug RM.Orthomyxoviridae: the viruses and their replication. In: Knipe DM, Howley, PM, Griffin DE, Martin MA, Lamb RA, Roizman B, et al., editors. Fields Virology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1487–503.

5. Influenza A virus M2 protein: monoclonal antibody restriction of virus growth and detection of M2 in virions.;Zebedee;J Virol,1988

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