Biomarkers of tolerance and immunological monitoring in liver transplantation-Reference-Cited by-同舟云学术

Biomarkers of tolerance and immunological monitoring in liver transplantation

Published:2020-06-18 Issue:2 Volume:12 Page:126-134
ISSN:2542-0909
Container-title:Transplantologiya. The Russian Journal of Transplantation
language:
Short-container-title:Transplantologiâ (Mosk.)

Author:

Syutkin V. E.¹^ORCID,Borovkova N. V.¹^ORCID,Novruzbekov M. S.¹^ORCID

Affiliation:

1. N.V. Sklifosovsky Research Institute for Emergency Medicine

Abstract

Introduction. We reviewed the literature data on clinical and laboratory parameters that allow predicting the development of operational tolerance in liver transplant recipients after their complete weaning from immunosuppressive therapy. The aim was to identify possible biomarkers of tolerance in liver transplant recipients with the successful complete weaning from immunosuppression for subsequent implementation in routine clinical practice. The cellular, humoral, and molecular markers of the liver transplant recipients who were completely withdrawn from immunosuppressive therapy without the development of graft dysfunction were estimated. The authors underlined the necessity of clinical trials for identifying biomarkers of the operational tolerance development.

Publisher

IPO Association of Transplantologists

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