PHENOMENON OF DEMIKHOV. The origin of the assisted circulation concept and its implementation (V.P. Demikhov, 1937–1947)

Author:

Glyantsev S. P.1ORCID,Werner A.2

Affiliation:

1. A.N. Bakoulev National Medical Research Center for Cardiovascular Surgery; N.A. Semashko National Research Institute of Public Health

2. Cardiothoracic Surgery Clinic, HELIOS Hospital Krefeld

Abstract

It is generally accepted that the concept of mechanical circulatory support originates from the USA in the 1960s and was implemented in the clinic by American surgeons S. Crawford, M. DeBakey, D. Cooley, D. Liotta and others by creating portable implantable pneumatic devices included in the cardiovascular system parallel to the biological heart to maintain its activity in heart failure. However, we found that twenty years earlier, in 1947, a similar concept was first put forward by the Soviet biologist and physiologist V.P. Demikhov, who had implemented it in an experiment by creating implantable electromechanical devices and transplanting a second, additional heart into the animal chest. At the same time, V.P. Demikhov suggested using his models both for maintaining the function of a weakened biological heart and for its recovery. Since an idea similar to that published in an English-language edition had never been formulated by anyone before V.P. Demikhov, his priority is global.

Publisher

IPO Association of Transplantologists

Subject

Transplantation,Immunology,Immunology and Allergy,Surgery

Reference16 articles.

1. Kulyabko AA. Dal'neyshie opyty ozhivleniya serdtsa; Ozhivlenie chelovecheskogo serdtsa. St. Petersburg: Tip. Imp. Akad. Nauk Publ.; 1902. (In Russ.).

2. Andreev FA. Opyty vosstanovleniya deyatel'nosti serdtsa, dykhaniya i funktsiy tsentral'noy nervnoy sistemy. Moscow: Tip. Vil'de Publ.; 1915. (In Russ.).

3. Bogopolsky PM, Glyantsev SP, Loginov DT. Sergey Sergeevich Bryukhonenko the creator of cardiopulmonary bypass (on the 125th anniversary of his birth). Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2016;9(6):74–82. (In Russ.). https://doi.org/10.17116/kardio20169674-82

4. Bogopolsky PM, Glyantsev SP. Nikolai N. Terebinsky and his contribution to heart surgery (to the 75th anniversary of the publication of the monograph "Materials for the study of open access to the atrioventricular valves of the heart"). Clinical and Experimental Surgery. Petrovsky Journal. 2015;3(9):5–17. (In Russ.).

5. Liotta D, Hall CW, Henly WS, Cooley DA, Crawford ES, DeBakey ME. Prolonged assisted circulation during and after cardiac or aortic surgery. Prolonged partial left ventricular bypass by means of intracorporeal circulation. References Am J Cardiol. 1963;12:399–405. PMID: 14064861 https://doi.org/10.1016/0002-9149(63)90235-2

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