Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries-Reference-Cited by-同舟云学术

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

Published:2000-08 Issue:8 Volume:18 Page:852-856
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Söderlind Eskil,Strandberg Leif,Jirholt Pernilla,Kobayashi Norihiro,Alexeiva Vessela,Åberg Anna-Maria,Nilsson Anna,Jansson Bo,Ohlin Mats,Wingren Christer,Danielsson Lena,Carlsson Roland,Borrebaeck Carl A.K.

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt0800_852.pdf

Reference40 articles.

1. Barbas, C.F., Kang, A.S., Lerner, R.A. & Benkovic, S.J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88, 7978–7982 (1991).

2. Clackson, T., Hoogenboom, H.R., Griffiths, A.D. & Winter, G. Making antibody fragments using phage display libraries. Nature 352, 624–628 (1991).

3. Marks, J.D. et al. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222, 581–597 (1991).

4. Barbas, C.F., Bain, J.D., Hoekstra, D.M. & Lerner, R.A. Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. Proc. Natl. Acad. Sci. USA 89, 4457–4461 (1992).

5. Hoogenboom, H.R. & Winter, G. By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. J. Mol. Biol. 227, 381–388 (1992).

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