β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng872z.pdf
Reference29 articles.
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3. Blakesley, V.A., Butler, A.A., Koval, A.P., Okubo, Y. & LeRoith, D. in The IGF System 143–164 (Humana, New Jersey, 1999).
4. De Meyts, P. et al. The insulin-like growth factor-I receptor structure, ligand-binding mechanism and signal transduction. Horm. Res. 42, 152–169 (1994).
5. Van Schravendijk, C.F., Foriers, A., Van den Brande, J.L. & Pipeleers, D.G. Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells. Endocrinology 121, 1784–1788 (1987).
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