A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1 transgenic mice for expression of hFIX-Reference-Cited by-同舟云学术

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A 16-bp RBE element mediated Rep-dependent site-specific integration in AAVS1 transgenic mice for expression of hFIX

Published:2009-02-26 Issue:5 Volume:16 Page:589-595
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Xu Z X,Chen J Z,Yue Y B,Zhang J Q,Li Z H,Feng D M,Ruan Z C,Tian L,Xue J L,Wang Q J,Jia W

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt20099.pdf

Reference25 articles.

1. Kotin RM, Linden RM, Berns KI . Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination. EMBO J 1992; 11: 5071–5078.

2. Chiorini JA, Yang L, Safer B, Kotin RM . Determination of adeno-associated virus Rep68 and Rep78 binding sites by random sequence oligonucleotide selection. J Virol 1995; 69: 7334–7338.

3. Srivastava A, Lusby EW, Berns KI . Nucleotide sequence and organization of the adeno-associated virus 2 genome. J Virol 1983; 45: 555–564.

4. Linden RM, Winocour E, Berns KI . The recombination signals for adeno-associated virus site-specific integration. Proc Natl Acad Sci USA 1996; 93: 7966–7972.

5. Linden RM, Ward P, Giraud C, Winocour E, Berns KI . Site-specific integration by adeno-associated virus. Proc Natl Acad Sci USA 1996; 93: 11288–11294.

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