CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting-Reference-Cited by-同舟云学术

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CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting

Published:2015-08-20 Issue:1 Volume:23 Page:108-112
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Courtney D G,Moore J E,Atkinson S D,Maurizi E,Allen E H A,Pedrioli D M L,McLean W H I,Nesbit M A,Moore C B T

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt201582.pdf

Reference22 articles.

1. Hsu PD, Lander ES, Zhang F . Development and applications of CRISPR-Cas9 for genome engineering. Cell 2014; 157: 1262–1278.

2. Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 2014; 343: 84–87.

3. Wang T, Wei JJ, Sabatini DM, Lander ES . Genetic screens in human cells using the CRISPR-Cas9 system. Science 2014; 343: 80–84.

4. Westra ER, Semenova E, Datsenko KA, Jackson RN, Wiedenheft B, Severinov K et al. Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition. PLoS Genet 2013; 9: e1003742.

5. Smith C, Abalde-Atristain L, He C, Brodsky BR, Braunstein EM, Chaudhari P et al. Efficient and allele-specific genome editing of disease loci in human iPSCs. Mol Ther 2014; 23: 570–577.

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